Bispyrene–Fluorescein Hybrid Based FRET Cassette: A Convenient Platform toward Ratiometric Time-Resolved Probe for Bioanalytical Applications

Analytical ChemistryDOI: 10.1021/ac502863m

Creation of Libraries of Recurring Mass Spectra from Large Data Sets Assisted by a Dual-Column Workflow

Analytical ChemistryDOI: 10.1021/ac502379x

Kinetic Adsorption Profile and Conformation Evolution at the DNA-Gold Nanoparticle Interface Probed by Dynamic Light Scattering

Analytical ChemistryDOI: 10.1021/ac502440h

A Device Architecture for Three-Dimensional, Patterned Paper Immunoassays

Lab Chip, 2014, Accepted ManuscriptDOI: 10.1039/C4LC00876F, PaperJeremy E. Schonhorn, Syrena C. Fernandes, Anjali Rajaratnam, Rachel N. Deraney, Jason P. Rolland, Charles R. MaceDiagnostic assays can provide valuable information about the health status…

Superhydrophobic-Oleophobic Ag Nanowire Platform: An Analyte-Concentrating and Quantitative Aqueous and Organic Toxin Surface-Enhanced Raman Scattering Sensor

Analytical ChemistryDOI: 10.1021/ac502955w

A Bubble-based Microfluidic Gas Sensor for Gas Chromatographs

Lab Chip, 2014, Accepted ManuscriptDOI: 10.1039/C4LC00892H, PaperAshrafuzzaman Bulbul, Hanseup KimWe report a new proof-of-concept bubble-based gas sensor for a gas chromatography system, which utilizes the unique relationship between the diameters of …

A Solvent Replenishment Solution for Managing Evaporation of Biochemical Reactions in Air-Matrix Digital Microfluidics Devices

Lab Chip, 2014, Accepted Manuscript
DOI: 10.1039/C4LC00703D, Paper
Mais J. Jebrail, Ron Renzi, Anupama Sinha, Jim Van De Vreugde, Carmen Gondhalekar, Cesar Ambriz, Robert J Meagher, Steven S Branda
Digital microfluidics (DMF) is a powerful technique for sample preparation and analysis for a broad range of biological and chemical applications. In many cases, it is desirable to carry out…
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Two-dimensional acoustic particle focusing enables sheathless chip Coulter counter with planar electrode configuration

Lab Chip, 2014, Accepted ManuscriptDOI: 10.1039/C4LC00982G, PaperCarl Grenvall, Christian Antfolk, Christer Zoffmann Bisgaard, Thomas LaurellThe field of cytometry has grown in scope and importance ever since the early 20th century with leaps in techno…

xMAP Array Microspheres Based Stem–Loop Structured Probes as Conformational Switches for Multiplexing Detection of miRNAs

Analytical ChemistryDOI: 10.1021/ac501989b

Multiwavelength Fluorescence Otoscope for Video-Rate Chemical Imaging of Middle Ear Pathology

Analytical ChemistryDOI: 10.1021/ac5030232

Development of a Simplified Microfluidic Injector for Analysis of Droplet Content via Capillary Electrophoresis

Analytical ChemistryDOI: 10.1021/ac502272q

Enhancing Sensitivity of Surface Plasmon Resonance Biosensors by Functionalized Gold Nanoparticles: Size Matters

Analytical ChemistryDOI: 10.1021/ac502637u

Single-Cell Western Blotting after Whole-Cell Imaging to Assess Cancer Chemotherapeutic Response

Analytical ChemistryDOI: 10.1021/ac502932t

Advanced Amperometric Respiration Assay for Antimicrobial Susceptibility Testing

Analytical ChemistryDOI: 10.1021/ac502554s

Quantitative Analysis of Gold Nanoparticles in Single Cells by Laser Ablation Inductively Coupled Plasma-Mass Spectrometry

Analytical ChemistryDOI: 10.1021/ac502438n

Tunable Reverse Electrodialysis Microplatform with Geometrically Controlled Self-assembled Nanoparticle Network

Lab Chip, 2014, Accepted ManuscriptDOI: 10.1039/C4LC01031K, PaperEunpyo Choi, Kilsung Kwon, Daejoong Kim, Jungyul ParkClean and sustainable energy generation from ambient environment is important not only for large scale systems but also for tiny elect…

Microwave-assisted liquid–liquid microextraction based on solidification of ionic liquid for the determination of sulfonamides in environmental water samples

An easy, quick and green method, microwave-assisted liquid–liquid microextraction based on solidification of ionic liquid was first developed and applied to the extraction of sulfonamides in environmental water samples. 1-Ethy-3-methylimidazolium he…

Simultaneous extraction and determination of various pesticides in environmental waters

A simple and rapid method was developed for the simultaneous analysis of nine different pesticides in water samples by gas chromatography with mass spectrometry. A number of parameters that may affect the recovery of pesticides, such as the type of so…

Enantioseparation and thermodynamic study of naphthalene derivatives, new melatoninergic agonists, on coated amylose [tris(S)-1-phenylethylcarbamate] stationary phase. Transposition to preparative scale

This work reports a high-performance liquid chromatography normal-phase methodology to elucidate enantiomers of naphthalene derivatives, evaluated as melatoninergic agonists. For this purpose four different polysaccharide based chiral stationary phases were evaluated, namely Chiralcel OD-H (cellulose tris-3,5-dimethylphenylcarbamate), Chiralcel OJ (cellulose tris-methylbenzoate), Chiralpak AD (amylose tris-3,5-dimethylphenylcarbamate) and Chiralpak AS (amylose tris-(S)-1-phenylethylcarbamate) with different alcoholic modifiers on different amounts in n-heptane. A temperature study was carried out, between 20 and 40 °C and the apparent thermodynamic parameters were calculated thanks to the Van’t Hoff linearization. For all compounds (except 3), ΔΔH° and ΔΔS° exhibited positive values ranging from 791.2 to 9999.3 J/mol and from 3.9 to 37.8 J/K/mol respectively, indicating entropically driven separations. Optimized conditions led to goof resolution of 2.37 for compound 1 on Chiralpak AS, with heptane–2-propanol 90:10 (v/v), at a temperature of 30 °C. Then they were transposed to the preparative scale for compound 1, generating 22 mg of each enantiomer with an 80% yield. The limits of detection and of quantification were determined to allow the calculation of the enantiomeric excess. They were found with very low values, equal to 0.32 and 1.05 µM and 0.33 and 1.11 µM, respectively, for peaks 1 and 2 of compound 1. Copyright © 2014 John Wiley & Sons, Ltd.

Capture of the Circulating Plasmodium falciparum Biomarker HRP2 in a Multiplexed Format, via a Wearable Skin Patch

Analytical ChemistryDOI: 10.1021/ac5031682