On-demand acoustic droplet splitting and steering in a disposable microfluidic chip

Lab Chip, 2018, Advance ArticleDOI: 10.1039/C7LC01083D, PaperJinsoo Park, Jin Ho Jung, Kwangseok Park, Ghulam Destgeer, Husnain Ahmed, Raheel Ahmad, Hyung Jin SungAn acoustofluidic device for on-demand droplet splitting and steering in a disposable mic…

Lab Chip, 2018, Advance Article
DOI: 10.1039/C7LC01083D, Paper
Jinsoo Park, Jin Ho Jung, Kwangseok Park, Ghulam Destgeer, Husnain Ahmed, Raheel Ahmad, Hyung Jin Sung
An acoustofluidic device for on-demand droplet splitting and steering in a disposable microfluidic chip.
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Lab on a Chip in 2017

Lab Chip, 2018, Advance ArticleDOI: 10.1039/C7LC90123B, EditorialThis Editorial summarizes recent news from Lab on a Chip and looks forward to further developments in 2018.To cite this article before page numbers are assigned, use the DOI form of citat…

Lab Chip, 2018, Advance Article
DOI: 10.1039/C7LC90123B, Editorial

This Editorial summarizes recent news from Lab on a Chip and looks forward to further developments in 2018.
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Electrochemical biosensor for cancer cell detection based on surface 3D micro-array

Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC01117B, PaperShaoqin Liu, Li An, Guangtong Wang, Yu Han, Tianchan Li, Peng JinThe detection of rare circulating tumour cells (CTCs) in the patients’ blood is crucial for the early diagnosis of cancer…

Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC01117B, Paper
Shaoqin Liu, Li An, Guangtong Wang, Yu Han, Tianchan Li, Peng Jin
The detection of rare circulating tumour cells (CTCs) in the patients' blood is crucial for the early diagnosis of cancer, highly precise cancer therapy and monitoring the therapeutic outcomes in...
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High-throughput Double Emulsion-based Microfluidic Production of Hydrogel Microspheres with Tunable Chemical Functionalities toward Biomolecular Conjugation

Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC01088E, PaperEric Y. Liu, Sukwon Jung, David A. Weitz, Hyunmin Yi, Chang-Hyung ChoiChemically functional hydrogel microspheres hold significant potential in a range of applications including biosensin…

Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC01088E, Paper
Eric Y. Liu, Sukwon Jung, David A. Weitz, Hyunmin Yi, Chang-Hyung Choi
Chemically functional hydrogel microspheres hold significant potential in a range of applications including biosensing, drug delivery, and tissue engineering due to their high degree of flexibility in imparting a range...
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Multi-size spheroid formation using microfluidic funnels

Lab Chip, 2018, Advance ArticleDOI: 10.1039/C7LC00970D, PaperM. Marimuthu, N. Rousset, A. St-Georges-Robillard, M. A. Lateef, M. Ferland, A.-M. Mes-Masson, T. GervaisWe present a microfluidic platform for automatic multi-size spheroid formation within …

Lab Chip, 2018, Advance Article
DOI: 10.1039/C7LC00970D, Paper
M. Marimuthu, N. Rousset, A. St-Georges-Robillard, M. A. Lateef, M. Ferland, A.-M. Mes-Masson, T. Gervais
We present a microfluidic platform for automatic multi-size spheroid formation within constant volume hanging droplets (HDs) from a single inlet loading of a constant cell concentration.
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Towards Microwave Imaging of Cells

Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC01251A, PaperMehmet Kelleci, Hande Aydogmus, Levent Aslanbas, Selcuk Oguz Erbil, Mehmet Selim HanayIntegrated detection techniques that can provide the morphological properties of cells are needed fo…

Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC01251A, Paper
Mehmet Kelleci, Hande Aydogmus, Levent Aslanbas, Selcuk Oguz Erbil, Mehmet Selim Hanay
Integrated detection techniques that can provide the morphological properties of cells are needed for the widespread use of lab-on-a-chip technology. Herein, we establish a theoretical and experimental framework to use...
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Cyclic olefin copolymer as an X-ray compatible material for microfluidic devices

Lab Chip, 2018, Advance ArticleDOI: 10.1039/C7LC00824D, PaperManuela Denz, Gerrit Brehm, Clement Y. J. Hemonnot, Heidi Spears, Andrew Wittmeier, Chiara Cassini, Oliva Saldanha, Eleonora Perego, Ana Diaz, Manfred Burghammer, Sarah KosterFabrication of X…

Lab Chip, 2018, Advance Article
DOI: 10.1039/C7LC00824D, Paper
Manuela Denz, Gerrit Brehm, Clement Y. J. Hemonnot, Heidi Spears, Andrew Wittmeier, Chiara Cassini, Oliva Saldanha, Eleonora Perego, Ana Diaz, Manfred Burghammer, Sarah Koster
Fabrication of X-ray compatible microfluidic devices by hot embossing, and characterization for small angle X-ray scattering.
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Cancer immunotherapy [small mu ]-environment LabChip: taking advantage of optoelectronic tweezers

Lab Chip, 2018, Advance ArticleDOI: 10.1039/C7LC00963A, PaperLing-Yi Ke, Zong-Keng Kuo, Yu-Shih Chen, Tsu-Yi Yeh, Minxiang Dong, Hsiang-Wen Tseng, Cheng-Hsien LiuAn OET-based LabChip was developed to provide a stable and static culture [small mu ]-envi…

Lab Chip, 2018, Advance Article
DOI: 10.1039/C7LC00963A, Paper
Ling-Yi Ke, Zong-Keng Kuo, Yu-Shih Chen, Tsu-Yi Yeh, Minxiang Dong, Hsiang-Wen Tseng, Cheng-Hsien Liu
An OET-based LabChip was developed to provide a stable and static culture [small mu ]-environment for cancer immunotherapy studies. The TiOPc-based OET facilitates the studies of cell-cell interaction resulting in apoptotic progress of cancer cells.
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A deep conical agarose microwell array for adhesion independent three-dimensional cell culture and dynamic volume measurement

Lab Chip, 2018, Advance Article
DOI: 10.1039/C7LC00832E, Paper
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Andreas R. Thomsen, Christine Aldrian, Peter Bronsert, Yi Thomann, Norbert Nanko, Nicolas Melin, Gerta Rucker, Marie Follo, Anca L. Grosu, Gabriele Niedermann, Paul G. Layer, Anja Heselich, Per G. Lund
Miniaturised conical measures for cell aggregates.
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Lab Chip, 2018, Advance Article
DOI: 10.1039/C7LC00832E, Paper
Open Access Open Access
Creative Commons Licence  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Andreas R. Thomsen, Christine Aldrian, Peter Bronsert, Yi Thomann, Norbert Nanko, Nicolas Melin, Gerta Rucker, Marie Follo, Anca L. Grosu, Gabriele Niedermann, Paul G. Layer, Anja Heselich, Per G. Lund
Miniaturised conical measures for cell aggregates.
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Impact of complex surfaces on biomicrorheological measurements using optical tweezers.

Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC01176H, PaperShu Zhang, Lachlan Gibson, Alexander Stilgoe, Timo A Nieminen, Halina Rubinsztein-DunlopThe characterisation of physical properties in biologically relevant processes and the development …

Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC01176H, Paper
Shu Zhang, Lachlan Gibson, Alexander Stilgoe, Timo A Nieminen, Halina Rubinsztein-Dunlop
The characterisation of physical properties in biologically relevant processes and the development of novel microfluidic devices for this purpose are experiencing a great resurgence at present. In many of measurements...
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A robust, portable and backflow-free micromixing device based on both capillary- and vacuum-driven flows

Lab Chip, 2018, Advance ArticleDOI: 10.1039/C7LC01077J, PaperYaguang Zhai, Anyang Wang, Domin Koh, Philip Schneider, Kwang W. OhA robust, portable and backflow-free micromixing device using capillary-driven bypassing and syringe-assisted vacuum-driven …

Lab Chip, 2018, Advance Article
DOI: 10.1039/C7LC01077J, Paper
Yaguang Zhai, Anyang Wang, Domin Koh, Philip Schneider, Kwang W. Oh
A robust, portable and backflow-free micromixing device using capillary-driven bypassing and syringe-assisted vacuum-driven pumping shows great promise for a variety of blood typing assays, agglutination-based assays and point-of-care or lab-on-a-chip testing applications.
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Converting Colour to Length Based on Coffee-Ring Effect for Quantitative Immunoassays Using a Ruler as Readout

Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC01127J, CommunicationDagan Zhang, Bingbing Gao, Yangtian Chen, Hong liuWe report a method for converting the colorimetric results of enzyme-link immunosorbent assay (ELISA) into length based on the co…

Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC01127J, Communication
Dagan Zhang, Bingbing Gao, Yangtian Chen, Hong liu
We report a method for converting the colorimetric results of enzyme-link immunosorbent assay (ELISA) into length based on the coffee-ring effect, so that the quantitative detection of analyte can be...
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Real-time two-photon-lithography in controlled flow to create a single-microparticle-array and particle-cluster-array for optofluidic imaging

Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC01080J, PaperBing Xu, Yang Shi, Zhao-Xin Lao, Jin-Cheng Ni, Guoqiang Li, Yanlei Hu, Jiawen Li, Jia-ru Chu, Dong Wu, Koji SugiokaMicroarray technology provides an excellent platform for biomedical and …

Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC01080J, Paper
Bing Xu, Yang Shi, Zhao-Xin Lao, Jin-Cheng Ni, Guoqiang Li, Yanlei Hu, Jiawen Li, Jia-ru Chu, Dong Wu, Koji Sugioka
Microarray technology provides an excellent platform for biomedical and biochemical research including basic scientific studies, drug-discovery, and diagnostics. Here, we develop a novel method referred to as real-time two-photon-lithography in...
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On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products

Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00797C, Paper
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kadi L. Saar, Yingbo Zhang, Thomas Muller, Challa P. Kumar, Sean Devenish, Andrew Lynn, Urszula Lapinska, Xiaoting Yang, Sara Linse, Tuomas P. J. Knowles
Single-layer lithography microfluidic devices for applying high and stable electric fields on chip.
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Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00797C, Paper
Open Access Open Access
Creative Commons Licence  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Kadi L. Saar, Yingbo Zhang, Thomas Muller, Challa P. Kumar, Sean Devenish, Andrew Lynn, Urszula Lapinska, Xiaoting Yang, Sara Linse, Tuomas P. J. Knowles
Single-layer lithography microfluidic devices for applying high and stable electric fields on chip.
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Cyclic Olefin Copolymer as an X-ray compatible material for microfluidic devices

Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00824D, PaperManuela Denz, Gerrit Brehm, Clement Hemonnot, Heidi M Spears, Andrew Wittmeier, Chiara Cassini, Oliva Saldanha, Eleonora Perego, Ana Diaz, Manfred Burghammer, Sarah KosterThe combination …

Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00824D, Paper
Manuela Denz, Gerrit Brehm, Clement Hemonnot, Heidi M Spears, Andrew Wittmeier, Chiara Cassini, Oliva Saldanha, Eleonora Perego, Ana Diaz, Manfred Burghammer, Sarah Koster
The combination of microfluidics and X-ray methods attracts a lot of attention from researchers as it brings together the high controllability of microfluidic sample environments and the small length scales...
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On-demand acoustic droplet splitting and steering in a disposable microfluidic chip

Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC01083D, PaperJinsoo Park, Jin Ho Jung, Kwangseok Park, Ghulam Destgeer, Husnain Ahmed, Raheel Ahmad, Hyung Jin SungOn-chip droplet splitting is one of fundamental droplet-based microfluidic unit opera…

Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC01083D, Paper
Jinsoo Park, Jin Ho Jung, Kwangseok Park, Ghulam Destgeer, Husnain Ahmed, Raheel Ahmad, Hyung Jin Sung
On-chip droplet splitting is one of fundamental droplet-based microfluidic unit operations to control droplet volume after production and increase operational capability, flexibility, and throughput. Various droplet splitting methods reported to...
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A robust, portable and backflow-free micromixing device based on both capillary- and vacuum-driven flows

Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC01077J, PaperYaguang Zhai, Anyang Wang, Domin Koh, Phil Schneider, Kwang W OhIn capillary- or vacuum-driven microfluidics, surge backflow events are common when merging or pumping two similar or dissi…

Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC01077J, Paper
Yaguang Zhai, Anyang Wang, Domin Koh, Phil Schneider, Kwang W Oh
In capillary- or vacuum-driven microfluidics, surge backflow events are common when merging or pumping two similar or dissimilar liquids together if a pressure difference exists between them. In this work,...
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Subnanometer structure and function from ion beams through complex fluidics to fluorescent particles

Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC01047H, PaperKuo-Tang Liao, Joshua Schumacher, Henri J. Lezec, Samuel M. StavisAnalytical separation with subnanometer resolution of fluorescent nanoparticles in a nanofluidic device.To cite this article …

Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC01047H, Paper
Kuo-Tang Liao, Joshua Schumacher, Henri J. Lezec, Samuel M. Stavis
Analytical separation with subnanometer resolution of fluorescent nanoparticles in a nanofluidic device.
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Fluorescence-Activated Droplet Sorting of Lipolytic Microorganisms Using a Compact Optical System

Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00993C, PaperYuxin Qiao, Xiaoyan Zhao, Jun Zhu, Ran Tu, Libing Dong, Li Wang, Zhiyang Dong, Qinhong Wang, Wenbin DuLipases are ubiquitous enzymes of great physiological significance that have been use…

Lab Chip, 2017, Accepted Manuscript
DOI: 10.1039/C7LC00993C, Paper
Yuxin Qiao, Xiaoyan Zhao, Jun Zhu, Ran Tu, Libing Dong, Li Wang, Zhiyang Dong, Qinhong Wang, Wenbin Du
Lipases are ubiquitous enzymes of great physiological significance that have been used extensively in multiple industries. Environmental microorganisms are a major source for the discovery of novel lipases with high...
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Wearable sensors: modalities, challenges, and prospects

Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00914C, Critical Review
Open Access Open Access
J. Heikenfeld, A. Jajack, J. Rogers, P. Gutruf, L. Tian, T. Pan, R. Li, M. Khine, J. Kim, J. Wang, J. Kim
Non-invasive wearable sensing technology extracts mechanical, electrical, optical, and chemical information from the human body.
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Lab Chip, 2017, Advance Article
DOI: 10.1039/C7LC00914C, Critical Review
Open Access Open Access
J. Heikenfeld, A. Jajack, J. Rogers, P. Gutruf, L. Tian, T. Pan, R. Li, M. Khine, J. Kim, J. Wang, J. Kim
Non-invasive wearable sensing technology extracts mechanical, electrical, optical, and chemical information from the human body.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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