The Inuence of Water on the Memory Effect of the amylose tris(3,5-dimethylphenyl carbamate) stationary phase

Publication year: 2010Source: Journal of Chromatography A, In Press, Accepted Manuscript, Available online 23 October 2010Joel, Putnam , Georges, GuiochonAcid/base modi_ers are sometimes used as additives in normal phase elution on columns packed with…

Publication year: 2010
Source: Journal of Chromatography A, In Press, Accepted Manuscript, Available online 23 October 2010

Joel, Putnam , Georges, Guiochon

Acid/base modi_ers are sometimes used as additives in normal phase elution on columns packed with CHIRALPAK R-AD R. These modi_ers a_ect enantioseparations in ways that are not yet fully understood for the lack of systematic studies. Shifts of the selectivity of certain pairs of enantiomers upon exposure of the column to these modi_ers is amply documented. Furthermore, once the modi_er has been removed from the mobile phase, the modi_ed selectivity remains, which has been named the Memory E_ect. After a column has been exposed to 1an eluent stream containing acidic/basic modi_ers, this particular column no longer separates certain enantiomeric pairs...

Current approaches to trace analysis of pharmaceuticals and personal care products in the environment

Publication year: 2010Source: Journal of Chromatography A, In Press, Accepted Manuscript, Available online 23 October 2010Wolfgang W., BuchbergerA large number of xenobiotics including pharmaceuticals and personal care products are continuously release…

Publication year: 2010
Source: Journal of Chromatography A, In Press, Accepted Manuscript, Available online 23 October 2010

Wolfgang W., Buchberger

A large number of xenobiotics including pharmaceuticals and personal care products are continuously released into the environment. Effluents from sewage treatment plants are well known to be the major source for introduction of pharmaceuticals and personal care products into the aquatic system. In recent years, reliable methods have been established for residue analysis of these pollutants down to low ng/L levels. In this review, the different approaches to their trace determination are reviewed with special attention being paid to sample preparation procedures, state-of-the-art high-performance separation methods hyphenated with mass spectrometry, and immunochemical methods.

Determination of perfluorochemicals in biological, environmental and food samples by an automated on-line solid phase extraction ultra high performance liquid chromatography tandem mass spectrometry method

Publication year: 2010Source: Journal of Chromatography A, In Press, Accepted Manuscript, Available online 23 October 2010Fabio, Gosetti , Ugo, Chiuminatto , Davide, Zampieri , Eleonora, Mazzucco , Elisa, Robotti , …A rapid on-line solid phase ex…

Publication year: 2010
Source: Journal of Chromatography A, In Press, Accepted Manuscript, Available online 23 October 2010

Fabio, Gosetti , Ugo, Chiuminatto , Davide, Zampieri , Eleonora, Mazzucco , Elisa, Robotti , ...

A rapid on-line solid phase extraction ultra high performance liquid chromatography tandem mass spectrometry method was developed for the identification and quantitation of nine perfluorinated compounds in matrices of environmental, biological and food interest.Pre-treatment, solid phase extraction, chromatographic and mass detection conditions were optimised, in order to apply the whole methodology to the analysis of different matrices. Particular attention was devoted to the evaluation of matrix effect and the correlated phenomena of ion enhancement or suppression in mass spectrometry detection. LOD and LOQ range from 3 to 15 ng L-1 and from 10 to 50 ng L-1, respectively. Method detection...